What is the best desk setup for a digital illustrator? Two monitors, one drawing tablet and a drawing desk? What else do you recommend?
Depending on how you work you might want a scanner to get your hand drawings into your editing software for colorization and stuff.
Other then that it's pretty much up to you - I have seen all kinds of setups from a single 17" monitor with a A5 size tablet up to a double Apple LED Cinema Display setup with a huge Vacom Cintiq.
It's more a question of budget and needs...